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Human Plateable Hepatocytes From Whole Livers

Product Name

Human Plateable Hepatocytes From Whole Livers

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Cat.No

ABC-TC4022

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Human plateable hepatocytes, with intact metabolic pathways and cofactors, are well-accepted as the ‘gold standard’ for both academic and commercial use for in vitro study of hepatic function and hepatotoxicity. As the major cells in the liver, hepatocytes play an important role in drug metabolism, detoxification and protein synthesis. Plateable cryopreserved human hepatocytes has been characterized with comparable metabolic activities and transporter activities to freshly isolated hepatocytes including P450 isoform activities and Phase I and Phase II metabolizing enzyme activities.
Why choose Human Plateable Hepatocytes from Whole Livers from AcceGen?
AcceGen Human plateable hepatocytes are isolated from whole livers. Cells are cryopreserved immediately after isolation. Cells are characterized with the ability to form highly confluent monolayer for at least 5 days. All human cryo-plateable hepatocytes are tested negative for HIV-1, HBV, HCV and other pathogens, and quality tested with proper morphology and enzymatic activities such as specific CYP activities or UGT and SULT activities.

Disease

Normal

Source Organ

Liver

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

For research use only
Plateable human hepatocytes are ideal cell culture model that can be routinely used for studying liver-specific functions, metabolism studies, pathway identifications, P450 induction, uptake and efflux transporter studies and hepatropic pathogens. Furthermore, plateable hepatocytes are favoured by drug development where human-specific drug metabolism, hepatobiliary drug transport, hepatotoxicity and drug toxicity can be assessed.

Key Features

– Backed by AcceGen advanced technology
– Cryopreserved for highest viability and plating efficiency
– Quality-tested for accurate results

Growth Conditions

37 ℃, 5% CO2

Cell Type

Hepatocyte

Growth Mode

Adherent

Product Type

Hepatic Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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