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Primary Cells

Human Umbillical Artery Smooth Muscle Cells

  • For research use only

Cat No.

ABC-TC3859

Product Type

Vascular Cells

Cell Type

Smooth Muscle Cell

Species

Human

Growth Conditions

37 ℃, 5% CO2

Source Organ

Umbillical Artery

Disease

Normal

Storage

Liquid Nitrogen

Human Umbillical Artery Smooth Muscle Cells from AcceGen are isolated from umbilical arteries, suitable for vascular biology, contraction, and remodeling.

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Description

Human Umbilical Artery Smooth Muscle Cells are primary cells derived from the smooth muscle layer of the umbilical artery. These cells are of mesenchymal origin and exhibit a spindle-shaped or elongated morphology. These cells produce extracellular matrix (ECM) components like collagen and elastin, contributing to vascular elasticity and mechanical strength, and they play a vital role in regulating vascular tone and blood flow through contractile activity, mediated by calcium-dependent signaling pathways. They express key SMC-specific markers, including alpha-smooth muscle actin (α-SMA), calponin, smooth muscle myosin heavy chain (SM-MHC), and transgelin/SM22α, which are essential for their contractile function and structural integrity. The cells are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.

Product Code

HUASMC

Species

Human

Cat.No

ABC-TC3859

Product Category

Primary Cells

Size/Quantity

1 vial

Cell Type

Smooth Muscle Cell

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Umbillical Artery

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Vascular Cells

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Human Umbilical Artery Smooth Muscle Cells are suitable for in vitro studies of vascular smooth muscle cell biology, including contractility, proliferation, migration, and extracellular matrix production. They provide a well-characterized cellular model for investigating smooth muscle–associated structural and functional properties under controlled experimental conditions. These cells may be used to examine cellular responses to biochemical stimulation, mechanical cues, or environmental changes, as well as to evaluate signaling pathway activity and gene expression patterns related to smooth muscle physiology.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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