Human Vaginal Epithelial Cells

Description

Human vaginal epithelial cells are derived from human vaginal tissue, typically sourced from healthy female donors, and play a key role in defending against sexually transmitted infections (STIs). These cells exhibit a stratified squamous epithelium morphology, forming layered sheets, and express specific proteins on basal and suprabasal surfaces. They secrete mucus glycoproteins, contributing to enzymatic defense, and display microfolds, microridges, and cell-cell adhesion structures. These cells are involved in immune responses, producing cytokines and chemokines through toll-like receptor signaling. Functionally, they maintain structural integrity and provide both physical and immunological defense mechanisms. Human vaginal epithelial cells have a normal diploid karyotype, and there is no evidence of mutations or malignancy.