For research use only
| Cat No. | ABC-TC3877 |
| Product Type | Hepatic Cells |
| Cell Type | Liver Cell |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Liver |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Human whole liver cells are derived from prenatal livers that have been dissociated into single cells and frozen.
Human Whole Liver Cells are a heterogeneous population primarily derived from the hepatic parenchyma and non-parenchymal compartments, including hepatocytes, Kupffer cells, hepatic stellate cells, liver sinusoidal endothelial cells, and cholangiocytes. Hepatocytes, the dominant functional units, typically exhibit polygonal morphology with abundant cytoplasm, prominent nuclei, and well-defined cell borders. Functionally, hepatocytes regulate metabolism (gluconeogenesis, lipid synthesis), detoxification (xenobiotic metabolism), and bile production. Kupffer cells mediate immune responses, stellate cells regulate fibrosis via extracellular matrix deposition, and cholangiocytes maintain bile duct integrity. Human Whole Liver Cells may express hepatocyte-associated markers such as alpha-1-antitrypsin (A1AT), cytochrome P450 (CYP) enzymes, and hepatocyte nuclear factors (HNFs), reflecting the presence of hepatocytes within the mixed liver cell population. The cells are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.
| Product Code | Human Whole Liver Cells, Total Liver Cells, Liver-Derived Mixed Cells, Primary Hepatic Cells |
| Species | Human |
| Cat.No | ABC-TC3877 |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | Liver Cell |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Liver |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Hepatic Cells |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Human Whole Liver Cells have broad applications in biomedical research, drug development, and regenerative medicine. These cells are widely used in drug metabolism and toxicity testing, as they express cytochrome P450 enzymes critical for xenobiotic metabolism, enabling accurate prediction of drug interactions and liver injury. Furthermore, human liver cells are essential in toxicology and mechanistic studies, helping identify biomarkers of drug-induced liver injury (DILI).
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).