For research use only
| Cat No. | ABC-TC0495 |
| Product Type | Mouse Sarcoma Cell Lines |
| Cell Type | Fibroblast |
| Species | Mouse |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Embryo |
| Disease | Normal |
| Product Code | KBALB; K-234; K234 |
K-BALB Cell Line from AcceGen, a mouse A31 Kirsten sarcoma derivative, tumorigenic and used for cancer research, viral superinfection, and oncology.
K‑BALB (also known as KBALB, K‑234 or K234) is a mouse fibroblast cell line derived from BALB/c embryo tissue and transformed by Kirsten murine sarcoma virus (Ki‑MSV), resulting in adherent fibroblast morphology and loss of contact inhibition typical of transformed cells. The line originates from the BALB/3T3 clone A31 background, and transformation with Ki‑MSV confers tumorigenic properties with altered growth control compared to its parental clone. Studies of membrane glycoconjugates in Ki‑MSV‑transformed BALB/3T3 cells demonstrate changes in glycolipid composition associated with the transformed phenotype, supporting the biological distinctiveness of this line. K‑BALB cells are also sensitive to induction of endogenous type C virus under certain stress conditions such as X‑irradiation, reflecting complex interactions between transformation and retrovirus expression. Evidence for specific metastatic behavior in vivo varies among related transformed clones and is not a defining feature of this cell line. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | KBALB; K-234; K234 |
| Species | Mouse |
| Cat.No | ABC-TC0495 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Fibroblast |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Embryo |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Sarcoma Cell Lines |
K‑BALB is used as an in vitro model of virus‑induced transformation and oncogenic signaling in mouse fibroblasts, particularly for studies of murine sarcoma virus (MSV) transformation and altered growth control. It supports investigation of cell proliferation, loss of contact inhibition, membrane glycoconjugate changes accompanying transformation, and interactions between transformation and endogenous retroviral elements. The line also serves in pharmacological and mechanistic assays exploring signaling pathways in transformed fibroblasts and comparative analyses with nontransformed BALB/3T3 and other sarcoma virus‑transformed lines.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
