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Product Code | KASUMI-3; KASUMI3; Kasumi3 |
Species | Human |
Cat.No | ABL-TC0325 |
Product Category | Tumor Cell Lines |
Size/Quantity | 1 vial |
Cell Type | Lymphoblast-like |
Shipping Info | Dry Ice |
Growth Conditions | 37 ℃, 5% CO2 |
Source Organ | Blood |
Biosafety Level | 1 |
Storage | Liquid Nitrogen |
Product Type | Human Leukemia Cell Lines |
Kasumi-3 is a human lymphoblast cell line that was originally isolated from a 57-year-old Asian male patient with acute myeloblastic leukemia. Kasumi-3 exhibits lymphoblast-like morphology and suspension culture properties. This cell line displays additional chromosomal abnormalities, including del(5)(q15), del(9)(q32), and add(12)(p11). Kasumi-3 is characterized by surface expression of CD7, CD4, CD13, CD33, CD34, HLA-DR, and c-Kit.
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Kasumi-3 cells are a valuable model for research into acute myeloblastic leukemia (AML) and immune disorders. They are particularly useful for studying the M0 subtype of AML and investigating the role of the EVI1 gene in leukemogenesis. In addition, their suitability for 3D culture systems allows researchers to model complex tissue environments and explore innovative therapeutic strategies in hematological and immunological research.