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MCF7 | ||||
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| Product Name | MCF7 | |||
| Price | Get Quote | |||
| Cat.No | ABC-TC0640 | Species | Human | |
| Size/Quantity | 1 vial | Biosafety Level | 1 | |
| Shipping Info | Dry Ice | Storage | Liquid Nitrogen | |
| Description | MCF7 is a human breast cancer cell line derived by pleural effusion from a breast cancer patient. It exhibits characteristics similar to differentiated mammary epithelium, including the ability to process estradiol through cytoplasmic estrogen receptors and form domes. These cells express the WNT7B oncogene and insulin-like
Why choose MCF7 from AcceGen? Choose MCF7 from AcceGen for breast cancer research due to their high quality and viability, sterility. AcceGen offers advanced cryopreservation techniques and maintains rigorous quality control measures, ensuring reliable and consistent performance of the cell line.
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| Citation Guide | When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID). Oh, Chung-Sik et al. “Effect of equipotent doses of propofol and sevoflurane on endoplasmic reticulum stress during breast cancer surgery.” Korean journal of anesthesiology vol. 75,6 (2022): 487-495. doi:10.4097/kja.21569 | |||
| Application | FOR RESEARCH USE ONLY The MCF7 cell line, with its substantial expression of estrogen receptor (ER) alpha, has played a crucial role in breast cancer research, particularly in studying the effects of estrogen. Additionally, MCF-7 cells express androgen, progesterone, and glucocorticoid receptors, allowing researchers to explore other steroid signaling pathways relevant to metastatic breast cancer treatment. The derivation and isolation of MCF-7 cells have led to fundamental advancements in our understanding of breast cancer, making it a cornerstone in studying both response and resistance to ER-targeted therapy. | |||
| Growth Conditions | 37 ℃, 5% CO2 | |||
| Product Type | Human Breast Cancer Cell Lines | |||
| Product Image |  | |||
growth factor binding proteins (IGFBP) BP-2, BP-4, and BP-5. The expression of intracellular adhesion molecule (ICAM-1) regulates colony formation and cell adhesion via NF-κB control. MCF7 cells are typically slow-growing and appear as loosely attached three-dimensional clusters, sometimes with floating viable cells. They may exhibit delayed attachment until after the first or second subculture, and should be treated as a mixed adherent and suspension cell line. Additionally, the growth of MCF7 cells can be hindered by tumor necrosis factor alpha (TNF alpha).- ONLINE INQUIRY
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