For research use only
| Cat No. | ABC-TC3931 |
| Product Type | Mouse Primary Cells |
| Cell Type | Fibroblast |
| Species | Mouse |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Lung |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Mouse lung fibroblasts, 2-week ICR mouse.
Mouse Lung Fibroblasts are primary cells isolated from the lung tissue of healthy mice. They display characteristic spindle-shaped morphology and adherent growth patterns, and contribute to pulmonary structure and function. Functionally, these murine pulmonary fibroblasts play a key role in synthesizing extracellular matrix components, maintaining lung architecture, and regulating inflammatory responses. Dysregulation of these cells has been implicated in pulmonary fibrosis, asthma, and chronic obstructive pulmonary disease (COPD). The cells express vimentin. These cells have limited proliferative capacity in vitro. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | Mouse Lung Fibroblasts, Murine Pulmonary Fibroblasts, Lung Stromal Cells (Mouse), Pulmonary Fibroblasts (Mouse) |
| Species | Mouse |
| Cat.No | ABC-TC3931 |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | Fibroblast |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Lung |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Mouse Primary Cells |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Mouse Lung Fibroblasts can be used as an in vitro cell model to study the pathogenesis of respiratory diseases and lung fibrosis, such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD), and asthma. The cells are particularly valuable for investigating their secretion of extracellular matrix proteins and pro-fibrotic cytokines in response to inflammatory stimuli or oxidative stress, allowing researchers to explore molecular pathways underlying lung tissue remodeling and fibrotic progression. This supports discovery research and molecular target identification related to fibrotic lung diseases and inflammatory respiratory disorders associated with dysregulated lung fibroblast function in tissue repair and pathological dysregulation.
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