For research use only
| Cat No. | ABC-TC0707 |
| Product Type | Human Leukemia Cell Lines |
| Cell Type | Lymphoblast |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Lymphocyte |
| Product Code | MT2; MT-2J; MT-2Org |
MT-2 T Cell Leukemia Cells are used in modeling HTLV-1–associated leukemogenesis, T cell transformation, and retroviral infection progression.
MT-2 is a human T-cell line established by immortalizing adult peripheral blood lymphocytes with human T-cell leukemia virus type 1 (HTLV-1). These suspension cells exhibit small to medium lymphoid morphology and express T-cell markers CD3 and CD25, indicative of activated helper T cells. MT-2 cells contain integrated HTLV-1 provirus, serving as a key model for investigating HTLV-1-driven transformation, viral replication, and adult T-cell leukemia/lymphoma (ATLL) pathogenesis. They secrete cytokines including IL-2 and display constitutive activation of NF-κB signaling. Due to their viral integration and immunological features, MT-2 cells are widely used in studies of retroviral oncogenesis, viral-host interactions, and immune regulation.
| Product Code | MT2; MT-2J; MT-2Org |
| Species | Human |
| Cat.No | ABC-TC0707 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Lymphoblast |
| Growth Mode | Non-adherent or Adherent on Poly-L-lysine Treated Plastic |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Lymphocyte |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Leukemia Cell Lines |
The MT-2 cell line exhibits phenotypic and functional characteristics similar to regulatory T cells (Tregs), making it a valuable model for studying Tregs biology. These cells harbor HTLV-1 and support HIV replication, providing a platform for investigating virus-host interactions. MT-2 cells are also essential for exploring viral tropism, which is important in clinical decision-making and treatment development for infectious diseases.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
