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Primary Cells

Rat Cortical Astrocytes

  • BSL

    1

  • 142
Different parts of the rat brain, including the cortex, hippocampus, and cerebellum, are dissociated enzymatically and mechanically into suspension of single cells. Next, the cells are seeded, and the astrocytes are enriched in vitro, using specific medium and cultural conditions.
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Species

Rat

Cat.No

ABC-TC4077

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Primary Cells
Size/Quantity

1 vial

Cell Type

Astrocyte

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Brain

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Rat Primary Cells

Description

Rat Cortical AstrocytesRat cortical astrocytes are derived from the rat cerebral cortex. These cells are astrocytes, and after primary culture, they are cryopreserved. Rat cortical astrocytes provide mechanical support and nutrients for neurons, clear waste, transmit information, and regulate synapses. Studies have shown that rat cortical astrocytes serve as promoting long-term recovery after brain injury, enhancing neuronal growth, synaptic plasticity, and neuronal regeneration. Repeated freezing and thawing should be avoided during the culture process.

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Citation

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Application

  • Rat cortical astrocytes are widely used in vitro to investigate the diverse functions of astrocytes in the nervous system. They support studies in neurogenesis, neurotransmitter activity, gene expression, signaling pathways, electrophysiology, neurotoxicity, and drug screening. These cells are also used to evaluate the neuroprotective potential of bioenergetic stabilizers in stroke models and to explore the role of astrocytes in regulating brain microvascular endothelial cells, particularly in the context of iron transport.

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