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Species | Rat |
Cat.No | ABC-TC4077 |
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Product Category | Primary Cells |
Size/Quantity | 1 vial |
Cell Type | Astrocyte |
Shipping Info | Dry Ice |
Growth Conditions | 37 ℃, 5% CO2 |
Source Organ | Brain |
Disease | Normal |
Biosafety Level | 1 |
Storage | Liquid Nitrogen |
Product Type | Rat Primary Cells |
Rat cortical astrocytes are derived from the rat cerebral cortex. These cells are astrocytes, and after primary culture, they are cryopreserved. Rat cortical astrocytes provide mechanical support and nutrients for neurons, clear waste, transmit information, and regulate synapses. Studies have shown that rat cortical astrocytes serve as promoting long-term recovery after brain injury, enhancing neuronal growth, synaptic plasticity, and neuronal regeneration. Repeated freezing and thawing should be avoided during the culture process.
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Rat cortical astrocytes are widely used in vitro to investigate the diverse functions of astrocytes in the nervous system. They support studies in neurogenesis, neurotransmitter activity, gene expression, signaling pathways, electrophysiology, neurotoxicity, and drug screening. These cells are also used to evaluate the neuroprotective potential of bioenergetic stabilizers in stroke models and to explore the role of astrocytes in regulating brain microvascular endothelial cells, particularly in the context of iron transport.