Primary Cells

Rat Cerebellum Neurons

  • For research use only

Cat No.

ABC-TC4112

Product Type

Rat Primary Cells

Cell Type

Neuron

Species

Rat

Growth Conditions

37 ℃, 5% CO2

Source Organ

Brain

Disease

Normal

Storage

Liquid Nitrogen

Rat Cerebellar Granular Cells are isolated from cerebellar cortex of adult Sprague Dawley rats at postnatal day 8.

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Description

Rat Cerebellum Neurons are primary neurons isolated from the cerebellum of rats. These neurons exhibit a complex morphology with well-developed dendritic arborization and elongated axonal projections, characteristic of mature cerebellar neurons. They play a key role in motor control, coordination, and cognitive functions, making them essential for neurobiological research. Upon isolation, these cells are cryopreserved immediately to maintain native morphology and functionality. Rat cerebellum neurons are ideal for studying neuronal signaling, synaptic plasticity, and cerebellar neurophysiology. These cells do not proliferate and are not recommended for passaging. Their applications span neurodegenerative disease models and functional studies related to cerebellar dysfunctions such as ataxia. They express typical neuronal marker βIII-tubulin (TUJ1). Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

Rat Cerebellum Neurons, Rat Cerebellar Neurons, Cerebellum Neurons

Species

Rat

Cat.No

ABC-TC4112

Product Category

Primary Cells

Size/Quantity

1 vial

Cell Type

Neuron

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Brain

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Rat Primary Cells

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Rat cerebellum neurons serve as an excellent in vitro model for studying cerebellar function, including motor coordination and synaptic communication. These cells are widely used in research related to neurodegenerative diseases, such as cerebellar ataxia and Parkinson’s disease. They are also valuable for investigating the mechanisms of neuroinflammation, neuronal excitability, and synaptic plasticity within cerebellar networks. Furthermore, these neurons are pivotal in studies of drug toxicity and neuroprotection, particularly for compounds targeting neuronal health in cerebellar-related disorders.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Frequently Asked Questions

  • Do these cells contain Purkinje cells? If so, what is the ratio compared to granule cells?

    Our rat primary cerebellum neurons (ABC-TC4112) are a highly enriched granule neuron population. We have not specifically quantified Purkinje cells in this preparation. However, based on GABA immunostaining, the proportion of GABA-positive cells is <5%. Since Purkinje cells are GABAergic neurons, the overall granule neuron purity is >95%, with GABAergic cells (potentially including very few Purkinje cells) accounting for less than 5%.

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