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Primary Cells

Rat Dermal Fibroblasts-fetal

  • For research use only

Cat No.

ABC-TC4122
Product Type

Rat Primary Cells
Cell Type

Fibroblast
Species

Rat
Growth Conditions

37 ℃, 5% CO2
Source Organ

Dermal
Disease

Normal
Storage

Liquid Nitrogen

Rat Primary Dermal Fibroblasts from AcceGen are isolated from tissue of Sprague-Dawley Rats.

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  • Rat Dermal Fibroblasts-fetal
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Home | Primary Cells | Animal Primary Cells | Rat Primary cells | Rat Dermal Fibroblasts-fetal

Description

Rat Dermal Fibroblasts-fetal are primary cells isolated from the dermal layer of fetal rat skin. These cells are cryopreserved at an early passage. They exhibit spindle-shaped morphology and adherent growth pattern in culture. Distinguishing them from neonatal and adult fibroblasts, these cells exhibit higher proliferative capacity and enhanced regenerative potential. They play a vital role in extracellular matrix (ECM) synthesis, wound healing, and tissue remodeling by secreting key structural proteins such as type I and type III collagen, fibronectin, and elastin. Rat fetal dermal fibroblasts express mesenchymal markers including vimentin and α-SMA. Due to their fetal origin, these cells display unique characteristics relevant for studying scarless wound healing and early developmental processes. The cells are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, mycoplasma, Fungi, Yeast and Bacteria.
Product Code

Rat Dermal Fibroblasts-Fetal, Rat Fetal Dermal Fibroblasts, Fetal Skin Fibroblasts
Species

Rat
Cat.No

ABC-TC4122
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Fibroblast
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Dermal
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Rat Primary Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Fetal rat dermal fibroblasts are particularly valuable for research into developmental skin biology, scarless wound healing, and enhanced regenerative mechanisms that differ significantly from adult fibroblast behavior. They are widely used in research on dermal regeneration, ECM remodeling, and scar formation. These cells also provide a relevant platform for evaluating anti-fibrotic drugs, biomaterials for skin grafts, and the cellular responses to inflammatory stimuli. Their responsiveness to growth factors such as TGF-β and FGF further enables exploration of signaling mechanisms involved in cutaneous fibrosis and tissue repair.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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