For research use only
| Cat No. | ABC-TC4173 |
| Product Type | Rat Primary Cells |
| Cell Type | Myeloid Cell |
| Species | Rat |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Myeloid |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Rat myeloid, 6-week Wistar rat.
Rat Myeloid Cells are primary cells isolated from 6-week-old Wistar rats, originating from hematopoietic stem cells (HSCs) in the bone marrow and differentiating through the myeloid progenitor pathway into granulocytes, monocytes, macrophages, and dendritic cells (DCs). These cells exhibit distinct features: granulocytes are characterized by segmented nuclei and cytoplasmic granules (neutral, eosinophilic, or basophilic), monocytes have large, kidney‑shaped nuclei, macrophages show vacuolated cytoplasm, and DCs feature dendritic processes. Rat myeloid cells are important in innate immunity (phagocytosis, pathogen killing), antigen presentation (DCs), and tissue homeostasis (macrophages). Key molecular markers include Ly6G (expressed by neutrophils), macrophage-associated markers such as F4/80 (expressed in a subset of macrophages), and CD11c (expressed on DCs). To ensure the quality of these primary cells, repeated freeze-thaw cycles are not recommended due to the fragile nature of these cells. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | Rat Myeloid Cells, Rat Myeloid Lineage Cells, Myeloid Cells |
| Species | Rat |
| Cat.No | ABC-TC4173 |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | Myeloid Cell |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Myeloid |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Rat Primary Cells |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Rat Myeloid Cells are widely utilized in biomedical research. In immunology, rat neutrophils and macrophages are employed to study innate immune responses, including phagocytosis, cytokine production, and pathogen clearance mechanisms, providing insights into sepsis and bacterial infections. The rat myeloid-derived suppressor cell (MDSC) model is particularly valuable in cancer research, where these cells suppress antitumor immunity via arginase-1 and reactive oxygen species (ROS), aiding in the development of immunotherapies.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
