For research use only
| Cat No. | ABC-TC4179 |
| Product Type | Rat Primary Cells |
| Cell Type | Neuron |
| Species | Rat |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Brain |
| Disease | Normal |
| Storage | Liquid Nitrogen |
The tissue of the central nervous system is made up of two classes of cells that may be broadly categorized as neurons and glia.
Rat Neurons-Raphe are primarily derived from the embryonic rat brain striatum. They mainly consist of serotonergic neurons, which are the most prominent cell types in the raphe nuclei. These neurons typically have a relatively large cell body with multiple dendrites that branch extensively, allowing for extensive synaptic connections. Their axons are long and project widely throughout the central nervous system, reaching various brain regions and the spinal cord. They play a crucial role in regulating mood, sleep-wake cycles, appetite, and pain perception by releasing serotonin. These cells express the neuronal marker β‑tubulin III. To ensure the quality of these primary cells, repeated freeze-thaw cycles are not recommended due to the fragile nature of these cells. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | Rat Neurons-Raphe, Rat Raphe Nuclei Neurons, Raphe Neurons |
| Species | Rat |
| Cat.No | ABC-TC4179 |
| Product Category | Primary Cells |
| Size/Quantity | 1 vial |
| Cell Type | Neuron |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Brain |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Rat Primary Cells |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Rat raphe nucleus neurons are extensively utilized in neuroscience research. These neurons serve as an essential in vitro model for investigating serotonin (5-HT) neurotransmission, enabling high-throughput screening of antidepressants, including SSRIs and novel compounds targeting 5-HT receptors. Their role in mood regulation and cognitive function makes them particularly valuable for studying depression, anxiety disorders, and schizophrenia, as well as neurodegenerative conditions like Alzheimer’s disease, where 5-HT dysfunction is implicated.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
