Rat Prostate Epithelial Cells

Description

Rat Prostate Epithelial Cells (RPECs) are specialized epithelial cells derived from the prostate gland of rats, primarily isolated from the ventral, dorsal, or lateral lobes. These cells are typically classified as luminal or basal epithelial cells based on their location and function within the gland. RPECs exhibit a cuboidal to columnar shape, forming organized monolayers with distinct cell-cell junctions. They play crucial roles in prostate secretion, maintaining glandular architecture, and responding to androgen signaling for secretory activity. Key molecular markers include CK18, ZO-1 and E-cadherin. To ensure the quality of these primary cells, repeated freeze-thaw cycles are not recommended due to the fragile nature of these cells. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.