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| Product Code | RIN m5F; Rin-M-5F; Rin-m-5F; RIN-m 5F; RINm-5F; RINm5F; RIN-m clone 5F; RIN Cl-5F; RIN-5F; Rin-5F; RIN 5F; RIN5F; m5F; 5F |
| Species | Rattus Norvegicus |
| Cat.No | ABC-TC0970 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Pancreas |
| Disease | Insulinoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Rat Pancreas Cancer Cell Lines |
RIN-5F is a rat pancreatic β-cell tumor cell line derived from the pancreatic islet β-cell tumor tissue of a male NEDH strain rat. This cell line exhibits epithelial-like morphology and adherent growth characteristics. RIN-5F cells robustly express key β-cell markers such as INS-2 (insulin) and GLUT2, along with genes involved in insulin secretion. The cells retain functional responsiveness to insulin signaling pathways. Due to these features, RIN-m5F is widely used in diabetes research, particularly in studies related to oxidative stress, drug protection mechanisms, and genetic modifications.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
RIN-5F cells serve as a valuable model for investigating pancreatic islet cell biology. They provide an effective platform for studying the mechanisms governing the synthesis, storage, and secretion of insulin and somatostatin, offering critical insights into endocrine regulation. This cell line’s physiological relevance makes it a powerful tool for research on diabetes, pancreatic islet function and other associated diseases including neuroendocrine tumors.
