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| Product Code | RIN m5F; Rin-M-5F; Rin-m-5F; RIN-m 5F; RINm-5F; RINm5F; RIN-m clone 5F; RIN Cl-5F; RIN-5F; Rin-5F; RIN 5F; RIN5F; m5F; 5F |
| Species | Rattus Norvegicus |
| Cat.No | ABC-TC0970 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Pancreas |
| Disease | Insulinoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Rat Pancreas Cancer Cell Lines |
RIN-5F is a derivative of the rat islet tumor cell line RIN-m, and it boasts distinctive features. These cells are renowned for their insulin secretion capacity and their high levels of the crucial APUD enzyme, L-dopa-decarboxylase. What sets them apart is their possession of membrane-bound secretory granules, facilitating insulin release, while interestingly, they do not produce somatostatin, unlike their parental line. During subculturing, these cells take approximately 3 days to attach fully, forming small clusters instead of a continuous monolayer. It is recommended to use a subcultivation ratio of 1:3 to 1:6, with medium renewal required every 3 to 4 days to sustain their growth.
Why choose RIN-5F from AcceGen?
RIN-5F cells from AcceGen exhibit exceptional features, boasting high viability and quality. These cells are meticulously incubated under optimal conditions and cryopreserved using advanced techniques, ensuring their robustness and longevity. They are delivered sterile and are rigorously quality-controlled, guaranteeing their reliability for a wide range of research applications.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
FOR RESEARCH USE ONLY
RIN-5F cells serve as invaluable models for investigating the intricacies of pancreatic islet cell biology. They provide a unique platform for delving into the mechanisms that govern the synthesis, storage, and secretion of insulin and somatostatin, shedding light on crucial aspects of endocrine regulation. This cell line’s ability to mimic these processes makes it an essential tool for research aimed at unraveling the mysteries of pancreatic islet function and associated diseases like diabetes and neuroendocrine tumors.
