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Tumor Cell Lines

TALL-1

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TALL-1 Cell Line is from human; Sex: M; Tissue: hemo-lymphocytic; Morphology: lymphocyte-like; Profile: leukemia, acute T lymphoblastic.
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Product Code

TALL 1; TALL1; T-ALL-1; T-ALL 1; T-ALL1; T-cell Acute Lymphoblastic Leukemia-1

Species

Human

Cat.No

ABL-TC0657

Product Category Tumor Cell Lines
Size/Quantity

1 vial

Cell Type

Lymphocyte-like

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Bone Marrow

Disease

Acute Lymphoblastic Leukemia

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Human Leukemia Cell Lines

Description

TALL-1
TALL-1 is a human leukemic T-cell line that was originally isolated from the bone marrow of a 28-year-old East Asian male patient with leukemic phase of T-cell lymphosarcoma. TALL-1 exhibits lymphoblast-like morphology and suspension culture properties with both spherical and rod-shaped forms. TALL-1 are considered as originated from the donor’s leukemic cells, its exhibits distinct T-lymphocyte characteristics and not carrying Epstein-Barr virus genome. The immunohistochemistry result are positive for CD2, cyCD3, CD4, CD7, and CD8, while negative for CD13, CD19, and CD34 for TALL-1.
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Citation

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Application

  • The TALL-1 cell line offers a valuable resource for researchers delving into the features and chemosensitivity of human leukemic T-cells. Its application extends to exploring pivotal elements in the advancement and progression of lymphoid malignancies, particularly T-ALL, shedding light on underlying mechanisms. Additionally, it aids in identifying essential genes in the molecular pathogenesis of human T-ALL, thereby offering insights into potential strategies for targeted therapeutic interventions.

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