Tumor Cell Lines

Detroit 562

  • For research use only

Cat No.

ABC-TC0208

Product Type

Human Skin Cancer Cell Lines

Species

Human

Growth Conditions

37 ℃, 5% CO2

Source Organ

Pharynx

Disease

Pharynx Cancer

Product Code

DETROIT 562; Detroit-562; Detroit562; DETROIT562; Det 562; Det. 562; Det562; D562

Leverage Detroit 562 cell line derived from pharyngeal carcinoma, useful for studying cancer pathogenesis and glucose metabolism in tumor cells.

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Description

Detroit 562 cell line is derived from a pleural effusion metastasis of pharyngeal carcinoma in an adult Caucasian female patient. This cell line displays an adherent growth pattern. These cells exhibit an epithelial-like morphology. Karyotype analysis shows chromosomal variability, which is common in cancer cells. The karyotype analysis reveals that the cell line has a modal chromosome number of 2n=46. They express NAT10, DCUN1D5, and GEMIN4. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

DETROIT 562; Detroit-562; Detroit562; DETROIT562; Det 562; Det. 562; Det562; D562

Species

Human

Cat.No

ABC-TC0208

Product Category

Tumor Cell Lines

Size/Quantity

1 vial

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Pharynx

Disease

Pharynx Cancer

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Human Skin Cancer Cell Lines

Application

  • Detroit 562 is widely used in virology due to its permissiveness to viruses such as poliovirus and vesicular stomatitis virus (VSV), serving as a model to study viral replication and antiviral drug development. In drug screening, this cell line helps evaluate chemotherapeutic agents and targeted therapies for head and neck squamous cell carcinoma (HNSCC), particularly those affecting EGFR and PI3K/AKT pathways.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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