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HighQC™ Human (Parental) Breast Cancer Stem Cell

Product Name

HighQC™ Human (Parental) Breast Cancer Stem Cell

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Cat.No

ABC-SC0136

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

The human (parental) breast cancer stem cell is a specialized cell derived from human breast cancer tissue. Within breast cancer, there exists a functional hierarchy of cells, where only a small subset of stem-like cells possess the ability to replenish and give rise to the differentiated cells that make up the bulk tumor. These tumorigenic breast cancer stem cells are notably abundant in cells displaying a CD44+/CD24-/low/epithelial-specific antigen (ESA)+ phenotype. Remarkably, as few as 100 cells exhibiting this specific phenotype have demonstrated the capability to form tumors in mice, while tens of thousands of cells with different phenotypes have failed to generate tumors.

 

Why choose Human (Parental) Breast Cancer Stem Cell from AcceGen?

Human (Parental) Breast Cancer Stem Cells from AcceGen are an ideal choice due to their exceptional quality and reliability. These cells are prepared under optimal conditions and undergo advanced cryopreservation techniques, ensuring high viability and quality upon thawing. With the ability to be passaged for up to 120 population doublings or 12 passages, they offer longevity for research purposes. AcceGen’s rigorous quality control measures guarantee sterile and reliable cells, while the shipment of a frozen vial of cells in dry ice ensures the delivery of one million viable cells.

Disease

Breast Cancer

Source Organ

Breast

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as "AcceGen Biotech Cat.# XXX-0000". In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

The applications of human (parental) breast cancer stem cells are significant in advancing our understanding and treatment of breast cancer. By being able to identify these tumorigenic cancer cells, researchers can explore the pathways that regulate their growth and survival, providing crucial insights into the disease. Moreover, since these cells are responsible for driving tumor development, targeting this specific population can lead to more effective therapies. The validation of cancer cell lines as models for studying the unique mechanisms of maintenance and survival in breast cancer stem cells also enables the development and testing of novel therapeutics, aiming to eradicate these harmful cells and improve patient outcomes.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Stem Cell

Growth Mode

Adherent

Product Type

Human Cancer Stem Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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