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Primary Cells

Human Muscle Myoblasts, Diabetes Type II

  • For research use only

Cat No.

ABC-TC3957

Product Type

Skeletal Muscle Cells

Cell Type

Myoblast

Species

Human

Growth Conditions

37 ℃, 5% CO2

Source Organ

Muscle

Disease

Diabetes Type II

Storage

Liquid Nitrogen

Human Muscle Myoblasts, Diabetes Type II support studies of insulin resistance, muscle regeneration, and metabolic dysfunction in diabetic skeletal muscle.

Product Image

Description

Human Muscle Myoblasts, Diabetes Type II are primary cells isolated from the skeletal muscle tissue of patients with Type II diabetes. These myogenic progenitor cells exhibit a spindle-shaped morphology with adherent growth. Functionally, these cells retain myotube differentiation potential, with altered proliferation and energy metabolism profiles under diabetic microenvironmental conditions, associated with type 2 diabetes-related muscle characteristics. They express desmin. Karyotype analysis shows normal diploidy. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

Human Muscle Myoblasts, Diabetes Type II, T2D Muscle Myoblasts, Type II Diabetic Myoblasts, Diabetic Skeletal Myoblasts (T2D)

Species

Human

Cat.No

ABC-TC3957

Product Category

Primary Cells

Size/Quantity

1 vial

Cell Type

Myoblast

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Muscle

Disease

Diabetes Type II

Storage

Liquid Nitrogen

Product Type

Skeletal Muscle Cells

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Human Muscle Myoblasts from Type II Diabetes patients provide a valuable in vitro tool for studying insulin-resistant myopathy and muscle degeneration. By examining their altered myotube differentiation, dysregulated glucose uptake, and inflammatory signaling profiles, researchers can explore related molecular pathways, supporting discovery research and target identification for metabolic disorder-associated muscle mechanisms.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
Prajitno JH, Pranoto A, Adiwinoto RD, Soelistijo SA. The effect of metformin on autophagy by LC3 expression in Type 2 Diabetes Mellitus (T2DM) human skeletal muscle cell culture. Bali Medical Journal. 2022;11(1):349-355. doi:10.15562/bmj.v11i1.3203
Prajitno JH, Pranoto A, Adiwinoto RD, Soelistijo SA. The effect of metformin on autophagy by LC3 expression in Type 2 Diabetes Mellitus (T2DM) human skeletal muscle cell culture. Bali Medical Journal. 2022;11(1):349-355. doi:10.15562/bmj.v11i1.3203

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