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Human Ovarian Surface Epithelial Cells

ImageAcceGen cells & cell lines
Product Name

Human Ovarian Surface Epithelial Cells

Product Code

HOSEpiC

Cat.No

ABC-TC3743

Species

Human

Biosafety Level

1

Size/Quantity

1 vial

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

The human ovary is covered with a single layer of flat to cuboidal surface epithelial cells (OSE). OSE are physiologically involved in follicular rupture and the subsequent repair of the follicle wall during reproductive age. OSE exhibit a gland formation in coculture with endometrial stromal cells in an estrogen-rich environment. The phenotypic plasticity of these cells shares a mesenchymal property when they are cultured on two layers of extracellular matrix and collagen gel. OSE are the source of epithelial ovarian carcinomas. Understanding the mechanisms that regulate OSE cell survival, apoptosis, and cell growth is of great clinical importance because an aberrant signaling of any of these pathways is likely to be involved in epithelial ovarian cancer.HOSEpiC from AcceGen Research Laboratories are isolated from human ovarian tissue. HOSEpiC are cryopreserved either at primary or passage one cultures and delivered frozen. Each vial contains >5×10^5 cells in 1 ml volume. HOSEpiC are characterized by immunofluorescent method with cytokeratine antibodies (CK-14, -18 and -19). HOSEpiC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HOSEpiC are guaranteed to further expand for over 5 population doublings in the conditions provided by AcceGen Research Laboratories.

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Citation Guide

If the product is used for publication, it should be cited in the publication as: "AcceGen Cat.# XXX-0000". In addition, click here to submit your paper’s PubMed ID (PMID) to get a $100 coupon.

Application

For research use only

Product Type

Female Reproductive Cells

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