Human Ovarian Surface Epithelial Cells

Human Ovarian Surface Epithelial Cells are primary cells derived from the outer layer of the human ovary. In vivo, they display a diverse morphology ranging from squamous to cuboidal to low columnar. These cells play an active role in cyclical ovulatory follicular rupture and subsequent repair. They express various peptide hormones, sex steroids, growth factors, and receptors. Notably, when co-cultured with endometrial stromal cells in an estrogen-rich environment, these cells exhibit gland formation. Moreover, when cultured on two layers of extracellular matrix and collagen gel, they demonstrate a mesenchymal property, reflecting their phenotypic plasticity.

Why choose Human Ovarian Surface Epithelial Cells from AcceGen?

Human Ovarian Surface Epithelial Cells from AcceGen are cryopreserved at passage one and supplied frozen, with each vial containing over 5×10⁵ cells in 1 ml volume. These cells are identified through immunofluorescence using antibodies targeting cytokeratin-18 and/or cytokeratin-19. They have been thoroughly screened and confirmed to be negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. Furthermore, they are guaranteed to undergo five population doublings under the specified AcceGen’s conditions.