For research use only
| Cat No. | ABC-TC0462 |
| Product Type | Human Leukemia Cell Lines |
| Cell Type | Epithelial-like |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Cervix |
| Disease | Cervix Cancer |
| Product Code | J 111; J111; JIII |
Originally established from acute monocytic leukemia, HeLa-contaminated
J-111 was originally reported as a human acute monocytic leukemia cell line established from the bone marrow of a 30-year-old female patient. However, authoritative cell line authentication studies have shown that J-111 is contaminated and completely overgrown by HeLa cells, making it genetically indistinguishable from HeLa and not representative of its originally reported leukemia origin. J-111 HeLa derivative therefore reflect the characteristics of HPV-related cervical adenocarcinoma. This cell line is included on the International Cell Line Authentication Committee (ICLAC) Register of Misidentified Cell Lines and should be interpreted with caution when used in research. The cells still grow as adherent epithelial monolayers in vitro and have been used in unrelated studies such as cellular motility and cytoskeletal structure investigations due to their HeLa origin. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | J 111; J111; JIII |
| Species | Human |
| Cat.No | ABC-TC0462 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial-like |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Cervix |
| Disease | Cervix Cancer |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Leukemia Cell Lines |
Due to its confirmed HeLa contamination, J-111 cells are applied as a general human epithelial carcinoma model (reflecting HeLa characteristics) for cell biology studies such as cytoskeletal dynamics, motility assays, and general epithelial cell behavior, rather than as a leukemia model. Users should authenticate identity before applying this line to disease-specific research.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
