For research use only
| Cat No. | ABC-TC0678 |
| Product Type | Human Bone Cancer Cell Lines |
| Cell Type | Fibroblast |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Bone |
| Disease | Osteosarcoma |
| Product Code | M-G63; MG63 |
MG-63 is a human osteosarcoma cell line with fibroblast-like morphology,hypotriploid karyotype, about 44% cells having 66 chromosomes, used in bone cancer.
MG-63 is a human osteosarcoma cell line derived from a moderately differentiated osteogenic sarcoma of a 14-year-old male patient. These cells exhibit an adherent growth pattern with a polygonal to spindle-shaped fibroblast-like morphology and can be continuously passaged in vitro. MG-63 cells display characteristics of immature osteoblasts, including the ability to produce alkaline phosphatase and type I collagen, important markers of bone formation. They express osteogenic genes such as osteocalcin, osteopontin, and runt-related transcription factor 2 (RUNX2), reflecting their osteoblastic lineage. Additionally, MG-63 cells secrete various growth factors and cytokines, making them widely used in bone biology, tumorigenesis, and drug screening studies. Their proliferative capacity and responsiveness to osteogenic stimuli contribute to their utility as an in vitro model for studying osteosarcoma and bone metabolism.
| Product Code | M-G63; MG63 |
| Species | Human |
| Cat.No | ABC-TC0678 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Fibroblast |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Bone |
| Disease | Osteosarcoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Bone Cancer Cell Lines |
MG-63 cells are commonly used as an osteoblast-like model to study bone cell viability, adhesion, and proliferation. They are particularly useful for investigating bone differentiation processes and the regulation of osteocalcin expression. These features make MG-63 cells essential for research into bone physiology, pathology, and therapeutic interventions related to skeletal disorders.
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