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Primary Cells

Mouse Intestinal Fibroblasts

  • For research use only

Cat No.

ABC-TC3929
Product Type

Mouse Primary Cells
Cell Type

Fibroblast
Species

Mouse
Growth Conditions

37 ℃, 5% CO2
Source Organ

Intestine
Disease

Normal
Storage

Liquid Nitrogen

Mouse intestinal fibroblasts, 2-week C57B mouse.

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  • Mouse Intestinal Fibroblasts
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Home | Primary Cells | Animal Primary Cells | Mouse Primary cells | Mouse Intestinal Fibroblasts

Description

Mouse Intestinal Fibroblasts are primary cells isolated from the intestinal tissue of healthy mice. They exhibit a typical spindle-shaped morphology with adherent growth. Functionally, these specialized mesenchymal cells play a key role in maintaining intestinal barrier integrity, synthesizing extracellular matrix components, and regulating inflammatory responses. Dysregulation of these cells is linked to inflammatory bowel diseases (IBD) like Crohn’s disease and ulcerative colitis. The cells express vimentin. These cells have limited proliferative capacity in vitro. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

Mouse Intestinal Fibroblasts, Murine Gut Fibroblasts, Intestinal Stromal Cells (Mouse), Mouse Enteric Fibroblasts
Species

Mouse
Cat.No

ABC-TC3929
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Fibroblast
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Intestine
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Mouse Primary Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Mouse Intestinal Fibroblasts serve as a relevant in vitro cellular model for investigating the pathophysiological processes of inflammatory bowel diseases (IBD), such as Crohn’s disease and ulcerative colitis. For example, by investigating their secretion of extracellular matrix proteins and pro-inflammatory cytokines in response to microbial or immune stimuli, researchers can explore molecular pathways underlying intestinal fibrosis and chronic inflammation. This supports discovery research and molecular target identification related to IBD and gastrointestinal fibrosis associated with dysregulated intestinal fibroblast function in tissue repair, excessive scarring and barrier dysfunction.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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