Rat cardiac fibroblasts, Neonatal

Description

Rat Cardiac Fibroblasts, Neonatal are primary mesenchymal cells isolated from healthy neonatal rat ventricular tissue. These cells exhibit a spindle-shaped morphology, plastic-adherent growth properties, and high proliferative capacity. As the most abundant non-myocyte cell type in the neonatal heart, they play a critical role in synthesizing and remodeling of extracellular matrix (ECM) components, particularly types I/III collagen, under both physiological and pathological conditions. Compared to adult cardiac fibroblasts, neonatal fibroblasts exhibit greater plasticity, enhanced responsiveness to growth factors, and more dynamic ECM remodeling capacity. They are positive for vimentin. These cells are cryopreserved at an early passage. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.