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Primary Cells

Rat Cardiac Microvascular Endothelial Cells, Neonatal

  • For research use only

Cat No.

ABC-TC4109

Product Type

Rat Primary Cells

Cell Type

Endothelial

Species

Rat

Growth Conditions

37 ℃, 5% CO2

Source Organ

Heart

Disease

Normal

Storage

Liquid Nitrogen

Rat Cardiac Microvascular Endothelial Cells, Neonatal support cardiac angiogenesis studies, endothelial barrier assays, and ischemia–reperfusion modeling.

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Description

Rat Cardiac Microvascular Endothelial Cells (RCMECs), Neonatal are primary endothelial cells isolated from neonatal rat heart tissue. These cells are derived from the capillaries of the cardiac microvascular network, which are crucial for heart function and vascular integrity. RCMECs exhibit typical endothelial cobblestone morphology and grow in monolayers, and they are characterized by their ability to form tight junctions and respond to inflammatory stimuli. These cells serve as an ideal in vitro model for studying microvascular function, cardiac diseases, and endothelial cell signaling. They express key endothelial markers such as CD31 (PECAM-1) and von Willebrand Factor (vWF). They are cryopreserved at early passages to preserve their phenotypic and functional stability. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.
Product Code

RCAECs

Species

Rat

Cat.No

ABC-TC4109

Product Category

Primary Cells

Size/Quantity

1 vial

Cell Type

Endothelial

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Heart

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Rat Primary Cells

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Neonatal rat cardiac microvascular endothelial cells (RCMECs) are widely used in cardiovascular research to model heart diseases and study vascular integrity in the cardiac microvasculature. These cells support investigations into endothelial barrier disruption, inflammatory responses, and angiogenic signaling within the cardiac environment. RCMECs are a valuable in vitro model for studies related to vascular function, cardiac repair mechanisms, and drug screening involving vascular-targeted approaches. Furthermore, RCMECs are instrumental in studies of the cardiovascular response to oxidative stress, inflammation, and hypoxia.

Citation

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