Rat Ovarian Smooth Muscle Cells

Description

Rat Ovarian Smooth Muscle Cells (OSMCs) are derived from the ovarian stroma, particularly surrounding follicles, blood vessels, and interstitial tissues. These cells are of mesenchymal origin and exhibit a spindle-shaped or elongated morphology with tapered ends, characteristic of smooth muscle cells (SMCs). They possess a central nucleus and abundant actin-myosin filaments, enabling their contractile function. OSMCs regulate ovarian hemodynamics and follicular dynamics through rhythmic contractions, facilitating ovulation and hormone transport. They also contribute to extracellular matrix remodeling and stromal rigidity. Key molecular markers include α-smooth muscle actin (α-SMA). To ensure the quality of these primary cells, repeated freeze-thaw cycles are not recommended due to the fragile nature of these cells. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.