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Tumor Cell Lines

A549

  • For research use only

Cat No.

ABC-TC0032

Product Type

Human Lung Cancer Cell Lines

Cell Type

Epithelial

Species

Human

Growth Conditions

37 ℃, 5% CO2

Source Organ

Lung

Disease

Lung Cancer

Product Code

A 549; A-549; NCI-A549; hA549

A549 cells model alveolar epithelial function and are ideal for evaluating lung carcinoma signaling, epithelial transport, and drug interactions.

Product Image

Description

The A549 cell line was established in 1972 from the lung adenocarcinoma of a 58-year-old Caucasian male. These hypotriploid alveolar basal epithelial cells have a modal chromosome number of 66, with occasional variations. A549 cells express keratin, synthesize lecithin, and contain unsaturated fatty acids. They are squamous and play a role in the diffusion of substances across the lung’s alveolar space. Genetically, A549 cells exhibit mutations in TP53, KRAS, and STK11, commonly associated with lung adenocarcinoma. The A549 cell line is tumorigenic, with low metastatic behavior reported in some studies. No viral infections like HPV, HIV, or EBV have been reported.
Product Code

A 549; A-549; NCI-A549; hA549

Species

Human

Cat.No

ABC-TC0032

Product Category Tumor Cell Lines
Size/Quantity

1 vial

Cell Type

Epithelial

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Lung

Disease

Lung Cancer

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Human Lung Cancer Cell Lines

Application

  • In drug development, the A549 cell line can be utilized for in vitro and in vivo testing of novel drugs, including xenograft lung cancer models. Furthermore, A549 cells can also be used in enzymatic studies to investigate cancer cell proliferation and the effects of insulin.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Inquiring A549

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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