Rat Renal Tubular Epithelial Cells

Description

Rat Renal Tubular Epithelial Cells (RTEpiC) are primary epithelial cells isolated from the renal tubules of pathogen-free Sprague-Dawley rats. These cells are essential components of the nephron, responsible for selective reabsorption of glucose, amino acids, ions, and water, as well as secretion of metabolic waste, reflecting the function of renal tubular epithelial cells. RTEpiC exhibit a classic cobblestone epithelial morphology and grow as adherent monolayers under standard culture conditions. They express epithelial markers such as E-cadherin and cytokeratins. RTEpiC are suitable for short-term expansion and experimental use under recommended protocols, making them valuable models for studying renal tubular epithelial cells in vitro. To ensure the quality of these primary cells, repeated freeze-thaw cycles are not recommended due to the fragile nature of these cells. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.