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Knockout Stable Cell Lines
The CRISPR/Cas9 system has been developed as the most popular method for genome editing in recent years. The engineered CRISPR/Cas9 technology consists of a single guide RNA (sgRNA) and a human codon optimized Cas9 nuclease. The sgRNA recognizes the genomic target via standard Watson–crick base pairing and acts as a scaffold for binding of the endonuclease Cas9. Then Cas9 protein introduces site-specific DSBs in the target DNA sequences. Besides, in the phase of target recognition, the protospacer adjacent motif (PAM) adjacent to the 3’ end of the DNA target site is indispensable. Finally, targeted mutations can be induced by nonhomologous end joining (NHEJ).
CRISPR-Cas9 is a genome-editing tool that is creating a buzz in the science world. It is faster, cheaper and more accurate than previous techniques of editing DNA and has a wide range of potential applications. Our scientists use the CRISPR CAS9 (CRISPR/Cas9) to knock out one or double genes to generate a KO cell line.
AcceGen is offering a series of gene knockout cell lines developed by the CRISPR/Cas9 system. These cell lines provide you with a convenient means to study gene functions. Use the Mutant Gene Nomenclature to search, if you cannot find the specific product in our database, AcceGen Custom Stable Cell Lines Service is committed to pave new ways to meet all your needs.
Cat.# | Name | Description | Stock | Price |
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ABC-KH0004 | Human A2ML1 knockout cell line | Human A2ML1 knockout cell line is edited by CRISPR/Cas9 technology. ...more | Custom | +inquiry |
ABC-KH0003 | Human A2M knockout cell line | Human A2M knockout cell line is edited by CRISPR/Cas9 technology. ...more | Custom | +inquiry |
ABC-KH0002 | Human A1CF knockout cell line | Human A1CF knockout cell line is edited by CRISPR/Cas9 technology. ...more | Custom | +inquiry |
ABC-KH0001 | Human A1BG knockout cell line | Human A1BG knockout cell line is engineered from HeLa cell line using our unique CRISPR/Cas9 technol...more | Custom | +inquiry |
ABC-K01612 | Human BBC3 (ΔTP53BS/ΔTP53BS) HCT116 Cell Line | Human BBC3 (ΔTP53BS/ΔTP53BS) HCT116 Cell Line is Homozygous knockout of TP53 binding site in BBC3 pr...more | Custom | +inquiry |
ABC-K01611 | Human BBC3 (ΔTP53BS/ΔTP53BS) DLD-1 Cell Line | Human BBC3 (ΔTP53BS/ΔTP53BS) DLD-1 Cell Line is Homozygous knockout of TP53 binding site in BBC3 pro...more | Custom | +inquiry |
ABC-K01615 | Human BBC3 (-/-) CDKN1A (-/-) HCT116 Cell Line | Human BBC3 (-/-) CDKN1A (-/-) HCT116 Cell Line is Double homozygous knockout of CDKN1A and BBC3 ...more | Custom | +inquiry |
ABC-K01614 | Human BBC3 (-/-) HCT116 Cell Line | Human BBC3 (-/-) HCT116 Cell Line is Homozygous knockout of BBC3 ...more | Custom | +inquiry |
ABC-K01613 | Human BBC3 (-/-) DLD-1 Cell Line | Human BBC3 (-/-) DLD-1 Cell Line is Homozygous knockout of BBC3 ...more | Custom | +inquiry |
ABC-K01595 | Human BAX (-/-) HCT116 Cell Line | Human BAX (-/-) HCT116 Cell Line is Homozygous knockout of BAX ...more | Custom | +inquiry |
ABC-K01349 | Human ATG7 (cKO+/-) DLD-1 Cell Line | Human ATG7 (cKO+/-) DLD-1 Cell Line is Heterozygous knockout of first ATG7 allele, conditional knock...more | Custom | +inquiry |
ABC-K01348 | Human ATG7 (+/-) DLD-1 Cell Line | Human ATG7 (+/-) DLD-1 Cell Line is Heterozygous knockout of ATG7 ...more | Custom | +inquiry |
ABC-K01250 | Human ASF1A (+CBP-DYKDDDDK/+) HCT116 Tagged Cell Line | Human ASF1A (+CBP-DYKDDDDK/+) HCT116 Tagged Cell Line is Heterozygous CBP-DYKDHD-G-DYKDHD-I-DYKDDDDK...more | Custom | +inquiry |
ABC-K01109 | Human ARID1A (Q456*/Q456*) HCT116 Cell Line | Human ARID1A (Q456*/Q456*) HCT116 Cell Line is Homozygous knockout of ARID1A by knockin of premature...more | Custom | +inquiry |
ABC-K01108 | Human ARID1A (Q456*/+) HCT116 Cell Line | Human ARID1A (Q456*/+) HCT116 Cell Line is Heterozygous knockout of ARID1A by knockin of premature s...more | Custom | +inquiry |
ABC-K00580 | Human AKT2 (-/-) HCT116 Cell Line | Human AKT2 (-/-) HCT116 Cell Line is Homozygous knockout of AKT2 ...more | Custom | +inquiry |
ABC-K00579 | Human AKT2 (-/-) DLD-1 Cell Line | Human AKT2 (-/-) DLD-1 Cell Line is Homozygous knockout of AKT2 ...more | Custom | +inquiry |
ABC-K00572 | Human AKT1 (-/-) AKT2 (-/-) HCT116 Cell Line | Human AKT1 (-/-) AKT2 (-/-) HCT116 Cell Line is Double homozygous knockout of AKT1 and AKT2 ...more | Custom | +inquiry |
ABC-K00571 | Human AKT1 (-/-) AKT2 (-/-) DLD-1 Cell Line | Human AKT1 (-/-) AKT2 (-/-) DLD-1 Cell Line is Double homozygous knockout of AKT1 and AKT2 ...more | Custom | +inquiry |
ABC-K00570 | Human AKT1 (-/-) HCT116 Cell Line | Human AKT1 (-/-) HCT116 Cell Line is Homozygous knockout of AKT1 ...more | Custom | +inquiry |