MDA-MB-175-VII

MDA-MB-175-VII is an epithelial-like cell line derived from the pleural effusion of a 56-year-old Black female with ductal carcinoma. Displaying aneuploid characteristics, the cells possess an XX/XXX/XXXX chromosome configuration, exhibiting a model chromosome count of 84 ranging from 82 to 89. With chromosomes predominantly in the hypertetraploid to near-tetraploid range, this cell line retains multiple copies of most normal chromosomes within its karyotype. Remarkably, MDA-MB-175-VII can form tumors when transplanted into nude mice, making it a valuable model for cancer research. For subculturing, the cells are diluted at split ratios ranging from 1:3 to 1:5 and treated with either 0.25% trypsin or trypsin/EDTA. The process is carried out at 37°C without CO₂ supplementation, or alternatively, in a non-vented flask with the lid securely closed.

Why choose MDA-MB-175-VII from AcceGen?

MDA-MB-175-VII cells from AcceGen offer high viability and quality, cultivated under expert supervision in optimal conditions. They are sterile, confirmed free of bacterial, yeast, mycoplasma, HIV, HBV, and HCV contamination. The cell line’s identity is verified through STR profiling, reflecting our commitment to stringent quality control measures.