Human Bladder Epithelial Cells

Human bladder epithelial cells are the primary cells isolated from the human urinary bladder. Human bladder epithelium is specialized lining epithelium consisting of 3-7 layers of cells, which are classified into three types: basal cells (cuboidal cells), intermediate cells (polygonal cells), and umbrella cells at the apical layer. In some points, human bladder epithelium cells are thought to transform from basal cells to intermediate cells, and then to umbrella cells; however, some studies also indicated that both basal cells and intermediate cells are the precursor cells that can differentiate into umbrella cells. Primary human bladder epithelial cells grow slowly: 10-14 days to fully recover from cryopreservation; 7-10 days to reach 70%-90% confluence in the subculture. The biomarkers of human bladder epithelium cells includes: CK5⁺, CK7⁺, CK8⁺, CK18⁺, P63⁺, E-cadherin⁺, Zona occludens 1 (ZO-1)⁺, and α-smooth muscle Actin^–.

Why choose Human Bladder Epithelial Cells from AcceGen?

Human bladder epithelial cells from AccGen were prepared with our rigorous standards and by professional operators to ensure high cell viability of more than 70% after thawing. All the procedures are precisely controlled in a sterile condition that all cells are negative for bacterial, fungal, and mycoplasma contamination.